What are tissue stimulators (biostimulators)? These are a substances that are injected beneath the skin surface to restore volume and improve the appearance of the skin. They work by stimulating your body’s own natural fibroblast (cells that create collagen and elastin) production.

Key Benefits:
  • Minimal down time
  • Quick treatment times
  • Minimal discomfort
Who is suitable for tissue stimulator injections? Biostimulator injections are designed for individuals who wish to restore volume in their face. They are a great alternative to dermal fillers. Areas that work well with these injections include temples, jowls and cheeks.
Main Contraindications:
  • Pregnancy and breast feeding
  • Skin diseases
  • Autoimmune diseases
  • Active viral infection
  • Certain bleeding disorders
  • Allergy to applied products
  • Taking antibiotics
  • Tendency to keloids
Is there downtime? Due to biostimulators being an injectable, most patients experience some form of bruising, this varies from patient to patient and depends on the area being treated and method of application. Swelling directly after is evident also.

Is it painful? We apply a topical anesthetic cream prior to injecting to enhance comfort levels more so. When the numbing cream wears off after the procedure, patients may experience some mild discomfort – cold compress can help to alleviate this.
How many treatments are required? The recommended number of treatments depends on the area being treated, product used and condition of patient's skin. Usually a course of 3 treatments is required with 2 to 4 weeks apart.
How long will it last? Results of these injections can last a couple of months, sometimes year. It depends, in example, on patient's lifestyle. Patients that undergo a maintenance treatment usually get longer-lasting results. It is a tissue regenerating treatment, not a dermal filler, so the results are visible after several weeks, sometimes months, after administration of the product.
Prior to treatment:
  • Avoid the use of supplements that may thin the blood, including aspirin.
  • Prescription medications must be cleared by your GP before ceasing.
  • Avoid alcohol 24 hours prior to procedure.

What happens dring treatment? Before we begin injecting, a topical anaesthetic cream will be applied to the area for couple of minutes, as this improve comfort levels. Once the area is numb, we disinfect the skin. Throughout the procedure, you may experience some stinging sensations and tenderness – this is very normal and will subside.
What happens immediately after treatment? Directly after the injections, the area may be slightly swollen, red and some bruising may be evident. Once the numbing cream wears off, you may experience some tenderness – a cold compress can be used to reduce pain levels. After the injections, your aftercare will involve use of post-surgical cream to speed up regeneration. You must avoid other treatments on the face for 2 weeks post treatment.
Things to avoid after treatment:
  • Make-up (24 hours)
  • Excessive exercises (3 to 5 days)
  • Very cold/hot temperatures, sauna and swimming pools (2 weeks)
  • Sunbeds (2 weeks)
What are the potential risks? Like all medical procedures, there are risks involved. The most common side effect is swelling and bruising.


  • Profhilo is not actually a dermal filler, it is a hyaluronic acid formulated with the new patented technology. Profhilo has been engineered for skin bio remodelling. Profhilo is free from impurities and additives hence greater safety and reduced side effects.
  • Very effectively stimulates production of both, a natural collagen and elastin to renew the skin from within.
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  • Profhilo delivers great results as a treatment on its own or in combination with other aesthetics treatments currently on offer.
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  • Profhilo technology, in addition to supporting Hydrolift® Action by integrating the levels of endogenous hyaluronic acid, is able to optimize the Hydrolift® Action thanks to the presence of the stabilized hybrid complexes.
  • Reduced inflammation comparing to a regular dermal filler.
  • Highly biocompatible: Profhilo is in fact, a highly purified natural hyaluronic acid which does not contain chemicals (cross-linking agents) to modify the structure, therefore reducing the risk of adverse reactions.
  • Bioremodeling
  • Thanks to its unique characteristics, Profhilo provides a new possibility to combat facial skin ageing: bio remodelling, or the ability to improve skin laxity.